マツザキ トモアキ   MATSUZAKI TOMOAKI
  松崎 和炯
   所属   関西医科大学  腎泌尿器外科学講座
   職種   助教
論文種別 原著(症例報告除く)
言語種別 英語
査読の有無 査読あり
表題 A randomized clinical trial evaluating the short-term results of ureteral stent encrustation in urolithiasis patients undergoing ureteroscopy: micro-computed tomography evaluation
掲載誌名 正式名:Scientific reports
略  称:Sci Rep
ISSNコード:20452322
掲載区分国外
巻・号・頁 11(1),pp.10337
著者・共著者 Yoshida T, Takemoto K, Sakata Y, Matsuzaki T, Koito Y, Yamashita S, Hara I, Kinoshita H, Matsuda T
発行年月 2021/05
概要 Although many ureteral stents are commercially available, the actuality of
encrustation is yet to be elucidated in humans. This study compared the Tria
Ureteral Stent with PercuShield and the Polaris Ultra Ureteral Stent with
HydroPlus Coating for short-term encrustation formation. Eighty-four patients,
who required ureteral stent placement after ureteroscopy, were randomized into
two stent groups. After stent removal on postoperative day 14, the encrustation
volume on the stent surface was measured by micro-computed tomography. The
primary outcome was the inner luminal encrustation volume. Secondary outcomes
were encrustation volume on the outer or total surfaces and occurrence of
adverse events. Clinical factors related to encrustation were also assessed as a
post-hoc analysis. Finally, of the 82 patients analyzed, 75 (91.5%) had
encrustation in the inner lumen of the stent. The difference in median inner
encrustation volume between the Tria and Polaris Ultra stents was comparable
(0.56 vs. 0.37 mm3, P = 0.183). There was no difference observed in the
encrustation volume on the outer/total surfaces and stent-related adverse
events. In both ureteral stents, the shaft body showed significant inner luminal
encrustation compared to the proximal or distal loop (all, P < 0.05).
Dyslipidemia (P = 0.027), elevated urine pH (P = 0.046), and crystalluria
(P = 0.010) were associated with encrustation formation. The Tria and Polaris
Ultra stents had similar efficacy for preventing encrustation in the short-term.
Further studies are required to compare their long-term patency.
DOI 10.1038/s41598-021-89808-x
PMID 33990648