ミヤサカ　ヨウコ   MIYASAKA YOKO   宮坂　陽子    所属   関西医科大学  内科学第二講座    職種   准教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Successful treatment of a patient with Graves' disease on hemodialysis complicated by antithyroid drug-induced granulocytopenia and angina pectoris.
掲載誌名	正式名：Thyroid 略　 称：Thyroid ISSNコード：10507256
巻・号・頁	7(4),pp.621-624
著者・共著者	Miyasaka Y, Yoshimura M, Tabata S, Shozu A, Nishikawa M, Iwasaka T, Inada M.
担当区分	筆頭著者,責任著者
発行年月	1997/08
概要	We report here a patient with recurrent Graves' disease on hemodialysis. She also suffered from angina pectoris, which was probably a manifestation of Graves' disease due to the increased oxygen demands in the presence of fixed coronary lesions. Although antithyroid drugs induced mild granulocytopenia, propylthiouracil (PTU) or methimazole (MMI) was not discontinued during the administration of granulocyte colony-stimulating factor (G-CSF). The patient received sodium iodine-131 therapy, and became euthyroid with no chest pain. To our knowledge, this is the first case that illustrated the usefulness of G-CSF for antithyroid drug-induced granulocytopenia prior to thyroid ablation for Graves' disease complicated with chronic renal failure and angina pectoris.
文献番号	9292952