ヒダカ　ヒロシ   HIDAKA HIROSHI   日高　浩史    所属   関西医科大学  耳鼻咽喉科・頭頸部外科学講座    職種   准教授
論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	査読あり
表題	The Na-K-Cl cotransporters in the rat cochlea: RT-PCR and partial sequence analysis.
掲載誌名	正式名：Biochemical and biophysical research communications 略　 称：Biochem Biophys Res Commun ISSNコード：0006291X/10902104
掲載区分	国外
巻・号・頁	220(2),pp.425-430
総ページ数	6
著者・共著者	Hidaka H, Oshima T, Ikeda K, Furukawa M, Takasaka T.
発行年月	1996/03
概要	Nonsensory epithelial cells of the mammalian cochlea contribute to the production of the endolymph. The presence as well as the function of the Na-K-Cl cotransporter has been suggested, but not yet been proved. To identify the Na-K-Cl cotransporter isoforms expressed in the cochlea, mRNA was extracted from the cochlear lateral wall. After reverse transcription, resulting cDNA was amplified by polymerase chain reaction (PCR) with primers specific for Na-K-Cl cotransporter isoforms. In the rat cochlear lateral wall, mRNA homologous to the mouse bumetanide-sensitive Na-K-Cl cotransporter (mBSC2) was detected. These results suggest that the basolateral localization of the cotransporter in the marginal cell is involved in the secretory process of the endolymph.
researchmap用URL	https://researchmap.jp/hirohiro1112/