ノナカ　マサヒロ   NONAKA MASAHIRO   埜中　正博    所属   関西医科大学  脳神経外科学講座    職種   教授
論文種別	原著(症例報告除く)
言語種別	英語
査読の有無	査読あり
表題	BDNF atelocollagen mini-pellet accelerates facial nerve regeneration.
掲載誌名	正式名：Brain research 略　 称：Brain Res ISSNコード：0006899300068993
巻・号・頁	849(1-2),pp.235-238
著者・共著者	Kohmura E, Yuguchi T, Yoshimine T, Fujinaka T, Koseki N, Sano A, Kishino A, Nakayama C, Sakaki T, Nonaka M, Takemoto O, Hayakawa T
発行年月	1999/12
概要	We investigated the effect of BDNF mini-pellet on the GAP-43 mRNA expression and functional status of facial nerve in a rat model of facial nerve transection and immediate repair. The facial function started to recover at 17 days in the placebo group and 14 days in the BDNF group. BDNF group had shorter period of increased GAP-43 mRNA expression than the placebo group. Topically applied BDNF may accelerate the facial nerve regeneration.
DOI	10.1016/s0006-8993(99)02163-0
PMID	10592308