タカハシ　カンジ   TAKAHASHI KANJI   髙橋　寛二    所属   関西医科大学  眼科学講座    職種   非常勤講師
言語種別	英語
発表タイトル	Case of Choroidal Melanoma with Massive Extraocular Extension through Sclera
会議名	European Association for Vision and Eye Research
学会区分	国際学会及び海外の学会
発表形式	ポスター掲示
講演区分	一般
発表者・共同発表者	◎Kimura M, Ogata N, Takahashi K, Shima C, Nishimura T
発表年月日	2008/10
開催地 （都市, 国名）	Portroz, Slovenia
学会抄録	EVER2008 Programme　book 63
概要	Abstract. Purpose: To report a case of choroidal melanoma with massive extraocular extension through the sclera. Case: A 64-year-old woman presented visual impairment in the right eye with a few months duration. On her first visit, her corrected visual acuity was 10/20 OD. Ocular examination revealed a raised choroidal mass behind the lens and the serous retinal detachment in the lower retina. The choridal mass showed a mushroom shaped solid lesion by an ultrasonography. The diagnosis of peripheral choroidal melanoma was confirmed by further examinations with the computed tomography, magnetic resonance imaging, and brain perfusion scintigraphy. Because systemic metastasis was not found, we proposed her the therapy with the enucleation. However, she refused the enucleation and wished to be followed without any treatments. Seven months after then, the tumor showed extraocular extension, and presented the invasion to the subconjunctiva through the sclera. Finally, her right eyeball was enucleated. Histopathologically, the tumor was determined as mixed cell malignant melanoma of the choroid. The eyeball was congested with tumor cells and the tumor showed massive extraocular extension through the sclera to the orbit. The intraocular tumor presented marked necrotic lesions that indicate rapid growth of the tumor. Conclusion: Choroidal melanoma extends rapidly, and resulted in extraocular extension through the sclera.