教員情報
資格・免許
専門領域
ホームページ URL・researchmap等
職歴(略歴)
公的委員会・協会等
学術雑誌掲載論文
著書
学会発表
研究の専門分野
研究テーマ
研究手法
(最終更新日:2024-11-21 05:05:06.436332)
ナカムラ カエ
NAKAMURA KAE
中村 加枝
所属
関西医科大学 生理学講座
職種
教授
■
資格・免許
医師 博士(医学)
■
専門領域
神経生理学
■
ホームページ URL・researchmap等
http://www3.kmu.ac.jp/psl2/member.html
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職歴(略歴)
1.
1997/05~2002/03
ピッツバーグ大学 Research Associate
2.
2002/04~2006/08
米国衛生国立研究所 Research Fellow
3.
2006/09~2007/02
ウィスコンシンマジソン大学 生理学教室 Assistant Scientist
4.
2007/04~2027/03
関西医科大学 医学部 教授
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公的委員会・協会等
1.
2019/04/01~
枚方市国民健康保険運営協議会 副議長
2.
2021/10/01~2122/03/31
科研費審査委員/日本学術振興会 審査委員
■
学術雑誌掲載論文
1.
原著(症例報告除く)
An easy-to-implement, non-invasive head restraint method for monkey fMRI 2024/01
2.
原著(症例報告除く)
Differential and temporally dynamic involvement of primate amygdala nuclei in face animacy and reward information processing 2024/01
3.
原著(症例報告除く)
Rewarding-unrewarding prediction signals under a bivalent context in the primate lateral hypothalamus 2023/04
4.
総説
様々な視点から意思決定を考察する 薬理学的な視点から 2022/10
5.
原著(症例報告除く)
Facial temperature and pupil size as indicators of internal state in primates. 2022/01
6.
総説
【意思決定と行動選択の神経科学】セロトニンと意思決定 2021/08
7.
原著(症例報告除く)
Novel characterization of subjective visual vertical in patients with unilateral spatial neglect 2021/02
8.
原著(症例報告除く)
Eye gaze differences in school scenes between preschool children and adolescents with high-functioning autism spectrum disorder and those with typical development. 2021/01
9.
総説
Multiple neuronal circuits for variable object-action choices based on short- and long-term memories. 2019/12
10.
原著(症例報告除く)
Identification of neuron-type specific promoters in monkey genome and their functional validation in mice. 2019/10
11.
原著(症例報告除く)
Encoding prediction signals during appetitive and aversive Pavlovian conditioning in the primate lateral hypothalamus. 2019/02
12.
原著(症例報告除く)
神経機能コンソーシアム 認知機能改善に向けた複合現実技術の臨床応用 2018/12
13.
総説
Toward a multiscale modeling framework for understanding serotonergic function 2017/09
14.
原著(症例報告除く)
アイマークレコーダーを用いた半側空間無視の評価 2017/09
15.
原著(症例報告除く)
Distinct Functions of the Primate Putamen Direct and Indirect Pathways in Adaptive Outcome-Based Action Selection 2017/08
16.
原著(症例報告除く)
Parsing Heterogeneous Striatal Activity. 2017/05
17.
原著(症例報告除く)
Spatiotemporal characteristics of gaze of children with autism spectrum disorders while looking at classroom scenes 2017/05
18.
原著(症例報告除く)
【予測・意思決定・情動の脳内計算機構-セロトニン研究の新展開-】 背側縫線核による報酬・嫌悪情報処理 2017/01
19.
原著(症例報告除く)
Characteristics of fast-spiking neurons in the striatum of behaving monkeys 2016/04
20.
原著(症例報告除く)
Appetitive and aversive information coding in the primate dorsal raphe' nucleus 2015/04
21.
原著(症例報告除く)
From ventral-medial to dorsal-lateral striatum: Neural correlates of reward-guided decision-making 2015/01
22.
原著(症例報告除く)
Functions and computational principles of serotonergic and related systems at multiple scales. 2014/03
23.
総説
意思決定・行動選択の神経科学 セロトニンと意思決定 2014/01
24.
原著(症例報告除く)
The role of the dorsal raphé nucleus in reward-seeking behavior 2013/08
25.
原著(症例報告除く)
Differential reward coding in the subdivisions of the primate caudate during an oculomotor task 2012/11
26.
原著(症例報告除く)
Differential Reward Coding in the Subdivisions of the Primate Caudate during an Oculomotor Task. 2012/11
27.
原著(症例報告除く)
A neural correlate of predicted and actual reward-value information in monkey pedunculopontine tegmental and dorsal raphe nucleus during saccade tasks. 2011/10
28.
原著(症例報告除く)
Serotonin and dopamine: Unifying affective, activational, and decision functions. 2011/01
29.
症例報告
Cerebromalacia with epilepsy and cortical blinedness in a laboratory Japanese macague ( Macaca fuscata). 2010/09
30.
原著(症例報告除く)
Coding of task reward value in the dorsal raphe nucleus. 2010/05
31.
その他
ドパミンとセロトニンによる報酬獲得行動の制御のメカニズム 2010/03
32.
総説
ドパミン-セロトニン相互関係による衝動性のコントロールの神経機構 2009/09
33.
原著(症例報告除く)
Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus. 2008/05
34.
総説
Basal Ganglia orient eyes to reward. 2006
35.
原著(症例報告除く)
Extended LATER model can account for trial-by-trial variability of both pre- and post-processes. 2006
36.
原著(症例報告除く)
Facilitation of saccadic eye movements by post-saccadic electrical stimulation in the primate caudate. 2006
37.
原著(症例報告除く)
Role of Dopamine in the Primate Caudate Nucleus in Reward Modulation of Saccades. 2006
38.
原著(症例報告除く)
Neuronal activity in macaque SEF and ACC during performance of tasks involving conflict. 2005
39.
原著(症例報告除く)
Emergence of rhythm during motor learning. 2004
40.
原著(症例報告除く)
Updating of the visual representation in monkey striate and extrastriate cortex during saccades. 2002/03
41.
総説
Central mechanisms of motor skill learning. 2002
42.
原著(症例報告除く)
Long-term retention of motor skill in macaque monkeys and humans. 2002
43.
原著(症例報告除く)
Characteristics of sequential movements during early learning period in monkeys. 2000
44.
原著(症例報告除く)
Visual, saccade related, and cognitive activation of single neurons in monkey extrastriate area V3A. 2000
45.
原著(症例報告除く)
Effects of local inactivation of monkey medial frontal cortex in learning of sequential procedures. 1999
46.
総説
Parallel neural networks for learning sequential procedures. 1999
47.
原著(症例報告除く)
Characteristics of a long-term procedural skill in the monkey. 1998
48.
原著(症例報告除く)
Differential roles of the frontal cortex, basal ganglia, and cerebellum in visuomotor sequence learning. 1998
49.
原著(症例報告除く)
Neuronal activity in medial frontal cortex during learning of sequential procedures. 1998
50.
原著(症例報告除く)
Differential roles of monkey striatum in learning of sequential hand movement. 1997
51.
原著(症例報告除く)
Anticipatory saccades in sequential procedural learning in monkeys. 1996
52.
原著(症例報告除く)
Learning of sequential movements in the monkey : Process of learning and retention of memory. 1995
53.
原著(症例報告除く)
The practice of consultation-liaison psychiatry in Japan. 1993
54.
原著(症例報告除く)
救命救急センターに収容された自殺企図者の実態. 1991
5件表示
全件表示(54件)
■
著書
1.
部分執筆
腹側線条体「脳科学辞典」 2019/09
2.
その他
ドパミン系とセロトニン系における報酬・コスト情報の統合「脳の高次機能システム 平成16-21年度 No.16068101」 2010
3.
部分執筆
大脳皮質―基底核連関と情報統合 手続き記憶と閉回路システムによるExecutive function.「Brain Medical」 2001
4.
部分執筆
Neural mechanisms for learning of sequential procedures., The Cognitive Neurosciences 1999
5.
部分執筆
Learning of sequential procedures in monkeys., The Acquisition of Motor Behavior in Vertebrates 1996
6.
部分執筆
Learning of sequential procedures in monkeys., Recent Advances in Clinical Neurophysiology 1996
7.
部分執筆
Neural mechanisms of sequential procedural learning., Integrative and Molecular Approach to Brain Function 1996
8.
部分執筆
Procedural learning in monkeys - possible roles of the basal ganglia., Perception, Memory, and Emotion: Frontier in Neuroscience 1996
9.
部分執筆
Role of the medial frontal cortex in sequential procedural learning., Brain Processes and Memory 1996
10.
部分執筆
Procedural learning in the monkey., Functions of the Cortico-Basal Ganglia Loop 1995
11.
部分執筆
せん妄の原因、せん妄と環境因子、アルコール離脱せん妄「救急スタッフのための精神科マニュアル」 1992
5件表示
全件表示(11件)
■
学会発表
1.
Antagonizing dopamine D1 and D2 receptors caused a delay in the initiation of hasty action and an excessive compromise on opportunity loss in monkeys foraging multiple rewards with time limits (ポスター掲示,一般) 2024/07/26
2.
ストレス強度によって起こるサルの行動変容と、それに対する大脳基底核の関与 (口頭,一般) 2024/03/22
3.
Neuronal representation of emotion in the monkey parabrachial nucleus (ポスター掲示,一般) 2023/11/12
4.
Differential and temporally-dynamic involvement of primate amygdala
nuclei for social and reward information processing (ポスター掲示,一般) 2023/11/11
5.
Modulation of time perception by the emotional context in primate (ポスター掲示,一般) 2023/08/03
6.
Systemic D1R and D2R antagonists administration arrested/accelerated action initiation in a time pressure-dependent manner in a monkey performing a multiple reward foraging task. (ポスター掲示,一般) 2023/08/03
7.
Differential and temporally dynamic involvement of primate amygdala nuclei for social
and reward information processing. (ポスター掲示,一般) 2023/03/15
8.
The primate model of decision making under stress (口頭,シンポジウム・ワークショップ パネル(指名)) 2022/07/02
9.
サル外側腕傍核における情動と認知行動の神経表現 (ポスター掲示,一般) 2022/07/02
10.
制限時間依存的な意思決定戦略切替えメカニズムを研究するためのサルの新規採餌課題 (ポスター掲示,一般) 2022/07/02
11.
Serotonin Brain and beyond (口頭,特別講演・招待講演など) 2021/11/29
12.
Characteristics of visuospatial analyses during the measure of subjective visual vertical in acute stroke patients. 2021/07/28
13.
Dominant processing of social, rather than reward information in the lateral nucleus of primate amygdala. 2021/07/28
14.
Dynamic interaction between emotional and cognitive signal in primate dorsal raphe nucleus. (口頭) 2021/07/28
15.
サル扁桃体の社会的情報と報酬情報の処理において、興奮性応答は抑制性応答よりも優位である (ポスター掲示,一般) 2020/07/29
16.
サル扁桃体内で異なる社会的情報処理と報酬情報処理 (ポスター掲示,シンポジウム・ワークショップ パネル(公募)) 2019/12/19
17.
Combined representation of emotional salience and decision signals in primate dorsal raphe nucleus. (ポスター掲示,一般) 2019/10/20
18.
Segregated and overlapped processing of social and reward information in primate amygdala (ポスター掲示,一般) 2019/10/20
19.
The role of primate striatum for decision making under different emotional context (口頭,シンポジウム・ワークショップ パネル(指名)) 2019/07/28
20.
Characteristics of subjective visual vertical in patients with unilateral spatial neglect (ポスター掲示,一般) 2019/07/26
21.
Combined representation of emotional arousal and decision signals in primate dorsal raphe nucleus. (ポスター掲示,一般) 2019/07/26
22.
Representation of social and emotional information in primate amygdala (ポスター掲示,一般) 2019/07/26
23.
Effects of Visual Cues on Subjective Visual Vertical in Unilateral Neglect Patients Might be Limited to a Slight Improvement in Postural Balance (ポスター掲示) 2019/06/11
24.
Role of dopamine in the primate caudate for the decision making under different emotional context. (ポスター掲示,一般) 2018/11/04
25.
Functional validation of macaque promoter in mouse brain (口頭,一般) 2018/07/28
26.
Differential roles of dopamine D1 and D2 receptor function in the primate caudate for decision making under aversive context (ポスター掲示,一般) 2018/07/26
27.
Dual processing in the primate dorsal raphe neurons for decision making under different mood (口頭,シンポジウム・ワークショップ パネル(その他)) 2018/07/17
28.
サル尾状核における報酬獲得と罰回避情報処理 (口頭,特別講演・招待講演など) 2018/03/30
29.
Dual Processing in the Primate Dorsal Raphe Nucleus for Choice Behavior under different Mood (ポスター掲示,一般) 2017/11/15
30.
意思決定行動の神経メカニズムの解明における情動の計測の試み (口頭,シンポジウム・ワークショップ パネル(指名)) 2017/10/10
31.
The role of dorsal raphe neurons for integration of reward information with emotional context. (口頭,シンポジウム・ワークショップ パネル(公募)) 2017/09/07
32.
Emotion signals in primate dorsal raphe nucleus are modulated under choice (ポスター掲示,一般) 2017/07/21
33.
Reward seeking and punishment avoiding by primate single caudate neurons (シンポジウム・ワークショップ パネル(指名)) 2017/07/20
34.
Same monoamines, but different neurotransmitters; dopamine and serotonin (口頭,特別講演・招待講演など) 2017/06
35.
Gaze behavior and joint attention in dynamic scenes of school classes by children with autistic spectrum disorders; an eye-tracking study for early diagnosis and intervention (ポスター掲示,一般) 2016/11
36.
Gaze behavior in movies of Japanese and arithmetic class scenes; an eye-tracking study for early diagnosis of children with ASD (ポスター掲示,一般) 2016/07
37.
The aversive stimulus affect decision making, modulate autonomic response and neuronal activity in the primate caudate
サルの意思決定、自律神経反応および線条体尾状核の情報処理に嫌悪刺激の存在が与える影響 (ポスター掲示,一般) 2016/07
38.
The physiological analysis of emotion-cognition interaction in reversal learning in macaque monkey
感情が学習に与える影響についての生理学的解析 (ポスター掲示,一般) 2016/07
39.
背側縫線核による報酬・嫌悪情報処理 (口頭,特別講演・招待講演など) 2016/03
40.
物質と脳 (口頭,特別講演・招待講演など) 2015/12
41.
The appetitive and aversive context modulates choice behavior, autonomic responses, and the neuronal activity in the primate caudate (ポスター掲示,一般) 2015/10
42.
The effect of bimodal value representation on goal directed behavior
and reflective choice in behaving macaque (ポスター掲示,一般) 2015/10
43.
経頭蓋磁気刺激法の逆橋渡し研究 (口頭,特別講演・招待講演など) 2015/09
44.
An integrated system for the quantitative measure of motivation and emotion in monkeys (ポスター掲示,一般) 2015/07
45.
The impact of aversive information on the choice behavior, autonomic responses, and the activity in the caudate in monkeys (ポスター掲示,一般) 2015/07
46.
自閉症スペクトラム障害児の視線滞留時間の検討 (口頭,一般) 2015/03
47.
背側線状核細胞による報酬・嫌悪情報処理
Appetitive and aversive information coding in the primate dorsal raphe nucleus. (口頭,シンポジウム・ワークショップ パネル(指名)) 2015/03
48.
Behavioral and physiological impacts of aversive information in the monkeys (ポスター掲示,一般) 2014/11
49.
嫌悪刺激による意思決定行動と尾状核の神経活動への影響
The behavioral and physiological impact of aversive information in the monkeys. (ポスター掲示,一般) 2014/09
50.
Neurons in the lateral hypothalamic area of cynomolgus monkeys may provide precursor signals for midbrain dopaminergic neurons in reward processing (口頭,一般) 2014/07
51.
Modulation of responses to the conditioned and unconditioned stimuli in the primate lateral
hypothalamic area by an aversive option in Pavlovian conditioning (ポスター掲示,一般) 2013/11
52.
Representation of the aversive information in the primate caudate. (ポスター掲示,一般) 2013/11
53.
Inclusion of an aversive option in the task attenuates responses to the conditioned and unconditioned stimuli in the primatate lateral hypothalamus area
サル視床下部外側野ニューロンの神経活動は嫌悪刺激の導入により抑制される (ポスター掲示,一般) 2013/06
54.
Representation of the aversive information in the primate caudate
サルの尾状核における嫌悪刺激に関わる情報の表現様式 (ポスター掲示,一般) 2013/06
55.
Coding of reward uncertainty in the primate lateral hypothalamic neurons (ポスター掲示,一般) 2012/10
56.
Differential reward coding in the dorsolateral and ventromedial part of the primate caudate (ポスター掲示,一般) 2012/10
57.
Neurons in the primate lateralhypothalamic area encode reward probability, uncertainty, andpredicted values. (一般) 2012/10
58.
Action control and value coding in the primate darsal raphe nucleus
サル背側縫線核における行動選択および価値の表象 (ポスター掲示,一般) 2012/09
59.
Uncertainty coding in the primate lateral hypothalamic area
サル視床下部外側野における不確かさのコーディング (ポスター掲示,シンポジウム・ワークショップ パネル(指名)) 2012/09
60.
集中治療室における意識障害患者の眼球運動測定の意義 (口頭,一般) 2012/07
61.
Comparison of neuronal signals for reward value in appetitive and aversive contexts in the primate lateral hypothalamus area (ポスター掲示,一般) 2011/11
62.
Neuronal activity in the primate dorsal raphe nucleus encodes positive and negative value (ポスター掲示,一般) 2011/11
63.
APPETITIVE AND AVERSIVE CODING BY THE PRIMATE DORSAL RAPHE NUCLEUS (口頭) 2011/09
64.
Cognitive control of response inhibition in the primate (ポスター掲示,一般) 2011/09
65.
Neuronal modulation in appetitive and aversive contexts in the primate lateral hypothalamus (ポスター掲示) 2011/09
66.
Neural processing of appetitive and aversive stimuli in the primate dorsal raphe nucleus. (ポスター掲示,一般) 2010/11
67.
Positive and negative reward value coding in the primate lateral hypothalamus. (ポスター掲示,一般) 2010/11
68.
サル視床下部外側野における報酬情報表現は部位により異なる
Rward-coding by the primate lateral hypothalamus is spatially distinct. (ポスター掲示,一般) 2010/09
69.
サル背側縫線核における報酬および嫌悪刺激の情報表現
Neuronal coding of rewarding and aversive stimuli in the primate dorsal raphe nucleus. (ポスター掲示,一般) 2010/09
70.
価値に基づく意思決定の神経機構―新たな展開
Role of basal ganglia for reward-dependent modulation of action; New perspectives on value-based decision making. (口頭,特別講演・招待講演など) 2010/09
71.
報酬および嫌悪刺激に対するカニクイザル背側縫線核ニューロンの応答 (口頭,一般) 2010/08
72.
Reward coding in the primate dorsal raphe nucleus (口頭,特別講演・招待講演など) 2010/07
73.
Value coding by the primate dorsal raphe nucleus (口頭,特別講演・招待講演など) 2010/07
74.
Cerebromalacia with Epilepsy and Cortical Blindness in an Experimental
Japanese Macaque (ポスター掲示,一般) 2010/06
75.
報酬獲得行動におけるドパミンとセロトニンの役割 (口頭,特別講演・招待講演など) 2009/12
76.
Coding of appetitive and aversive value in the primate dorsal raphe nucleus (口頭) 2009/11
77.
セロトニンとドパミンによる報酬情報処理のメカニズム (口頭,特別講演・招待講演など) 2009/11
78.
Positive and negative value coding in the primate dorsal raphe nucleus (口頭) 2009/10
79.
Reward coding by the primate dorsal raphe neurons is context dependent. (ポスター掲示,一般) 2009/09
80.
Reward-dependent modulation of neuronal activity in the primate ventral striatum. (ポスター掲示,一般) 2009/09
81.
ドパミンとセロトニンによる報酬獲得行動の制御のメカニズム (口頭,特別講演・招待講演など) 2009/08
82.
ドパミン・セロトニンと大脳基底核による報酬獲得行動の発現 (口頭,特別講演・招待講演など) 2009/07
83.
動機・罰と行動~感情が運動をあやするしくみ (口頭,特別講演・招待講演など) 2009/05
84.
ドパミン系とセロトニン系における報酬・コスト情報の統合 (口頭) 2008/12
85.
縫線核による運動制御と意思決定. (口頭,特別講演・招待講演など) 2008/08
86.
Reward-dependent modulation of neuronal activity in the primate dorsal raphe nucleus. (口頭,特別講演・招待講演など) 2008/03
87.
Neuronal Activity of the Primate Dorsal Raphe Nucleus in the Biased Reward Saccade Tasks. (口頭,シンポジウム・ワークショップ パネル(指名)) 2007/11
88.
セロトニンとドパミンによる報酬情報処理のメカニズム. (口頭) 2007/11
89.
Differential reward coding by dorsal raphe neurons and dopamine neurons. (口頭,シンポジウム・ワークショップ パネル(指名)) 2007/10
90.
大脳基底核における報酬情報による行動変化のメカニズム. (口頭,一般) 2007/08
91.
Activation and inactivation of dopaminergic input to primate caudate-What will happen to the reward-seeking behavior. (口頭,一般) 2007/07
92.
報酬獲得行動におけるDopamineとSerotoninニューロンの神経活動の比較. (口頭,一般) 2007/06
93.
報酬の予測と評価における基底核線条体、黒質緻密部、および背側縫線核の役割. (口頭,特別講演・招待講演など) 2007/01
94.
Reward dependent modulation of neuronal activity in the primate dorsal raphe nucleus. (ポスター掲示,一般) 2006/10
95.
Effects of relative and absolute magnitudes of reward on saccadic eye movement and caudate neuronal activity in monkeys. (口頭,一般) 2005/11
96.
Manipulating reward contingency in the oculomotor region of primate caudate nucleus. (口頭,特別講演・招待講演など) 2005/02
97.
Manipulating reward signal in the oculomotor region of primate caudate nucleus. (口頭,特別講演・招待講演など) 2005/01
98.
Electrical stimulation in the primate caudate modulates saccadic eye movements -- a possible involvement of reinforcement learning. (口頭,特別講演・招待講演など) 2004/10
99.
Reward-dependent saccade bias is attenuated by local application of dopamine antagonist in the primate caudate nucleus. (ポスター掲示,一般) 2004/10
100.
Electrical stimulation in the primate caudate nucleus reinforces saccadic eye movement. (ポスター掲示,一般) 2003/11
101.
Error signal in monkey anterior cingulate cortex during performance of oculomotor task with conflict. (ポスター掲示,一般) 2002/11
102.
Effect of conflict on neuronal activity in monkey medial frontal cortex. (口頭,特別講演・招待講演など) 2002/01
103.
Classification of supplementary eye field and prefrontal neurons into categories based on temporal pattern of activity. (一般) 2001/11
104.
Effect of conflict on distinct classes of neurons in the supplementary eye field and prefrontal cortex. (ポスター掲示,一般) 2001/11
105.
Bridging between neuronal activity and voluntary behavior. (口頭,特別講演・招待講演など) 2001/09
106.
Performance of monkeys on oculomotor tasks involving stimulus-response incompatibility. (一般) 2000/11
107.
Updating of the visual representation in monkey striate and extrastriate cortex during saccades. (一般) 1999/10
108.
Orbital position effects on visual and saccade-related activity in monkey area V3A. (一般) 1998/11
109.
Visual, cognitive, and saccade-related activity of monkey area V3A neurons. (一般) 1998/11
110.
Activity of pre-SMA neuron for the performance of sequential movement in monkeys. (一般) 1997/10
111.
Effects of SMA and pre-SMA inactivation on learning of sequential movements in monkey. (一般) 1996/11
112.
Effects of SMA and pre-SMA inactivation on procedural learning in monkey. (一般) 1996/07
113.
Neuronal activities in medial premotor area of monkey during learning of sequential movements. (一般) 1995/11
114.
Anticipatory saccade in procedural learning. (一般) 1994/11
115.
Effects of the blockade of monkey basal ganglia on the procedural learning and memory. (一般) 1994/11
116.
Deficits in execution and learning of eye/hand movements by reversible blockade of the monkey striatum. (一般) 1993/12
117.
Role of anticipatory eye movement in procedural learning. (一般) 1993/12
5件表示
全件表示(117件)
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研究の専門分野
神経科学一般
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研究テーマ
1.
1987/06
1991/03
多発外傷の治療方針
実施形態:機関内共同研究
2.
1991/04
1993/03
ICUにおけるせん妄の発症機序と治療
実施形態:機関内共同研究
3.
1991
手続き記憶の神経機構
実施形態:機関内共同研究
4.
1997
視覚と眼球運動の関係
実施形態:国際共同研究
5.
2002
報酬獲得行動の神経メカニズム
実施形態:国際共同研究
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研究手法
神経生理学 神経薬理学