教員情報
資格・免許
専門領域
学術雑誌掲載論文
著書
学会発表
研究の専門分野
研究手法
(最終更新日:2025-02-11 05:05:06.943336)
マツムラ シンジ
MATSUMURA SHINJI
松村 伸治
所属
関西医科大学 病態分子イメージングセンター
職種
准教授
■
資格・免許
博士(理学)
■
専門領域
神経生物学
■
学術雑誌掲載論文
1.
総説
最先端医療の今 内臓痛特有の痛みをもたらす脊髄後角神経回路の探索 2024/07
2.
原著(症例報告除く)
Brn3a controls the soma localization and axonal extension patterns of developing spinal dorsal horn neurons 2023/09
3.
原著(症例報告除く)
Involvement of Brn3a-positive spinal dorsal horn neurons in the transmission of visceral pain in inflammatory bowel disease model mice 2022/12
4.
原著(症例報告除く)
Stiripentol alleviates neuropathic pain in L5 spinal nerve-transected mice 2020/06
5.
原著(症例報告除く)
Diabetic neuropathy research: from mouse models to targets for treatment. 2019/07
6.
原著(症例報告除く)
Two isoforms of cyclic GMP-dependent kinase-I exhibit distinct expression patterns in the adult mouse dorsal root ganglion. 2018/08
7.
原著(症例報告除く)
Impaired peripheral nerve regeneration in type-2 diabetic mouse model. 2018/01
8.
原著(症例報告除く)
Na+ /K+ -ATPase coupled to endothelin receptor type B stimulates peripheral nerve regeneration via lactate signalling 2017/09
9.
原著(症例報告除く)
RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury 2017/05
10.
原著(症例報告除く)
Role of c-Jun N-terminal kinase in late nerve regeneration monitored by in vivo imaging of thy1-yellow fluorescent protein transgenic mice 2016/02
11.
原著(症例報告除く)
Comparison of mechanisms of allodynia induced by acromelic acid A between early and late phases 2015/08
12.
原著(症例報告除く)
In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model 2015/04
13.
原著(症例報告除く)
Three-dimensional distribution of sensory stimulation-evoked neuronal activity of spinal dorsal horn neurons analyzed by in vivo calcium imaging 2014/08
14.
原著(症例報告除く)
The action site of the synthetic kainoid (2S,3R,4R)-3-carboxymethyl-4-(4-methylphenylthio)pyrrolidine-2-carboxylic acid (PSPA-4), an analogue of Japanese mushroom poison acromelic acid, for allodynia (tactile pain 2013/06
15.
原著(症例報告除く)
Involvement of Tyr1472 phosphorylation of NMDA receptor NR2B subunit in postherpetic neuralgia in model mice. 2012/08
16.
原著(症例報告除く)
Novel Strategy for the Control of Postoperative Pain: Long-Lasting Effect of an Implanted Analgesic Hydrogel in a Rat Model of Postoperative Pain. 2012/06
17.
総説
痛みとしびれのサイエンス-基礎と臨床 第1章:痛み,しびれのメカニズム, 痛みの可塑性と慢性化 2011/05
18.
原著(症例報告除く)
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord. 2011/02
19.
原著(症例報告除く)
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury. 2010/10
20.
原著(症例報告除く)
Impairment of CaMKII activation and attenuation of neuropathic pain in mice lacking NR2B phosphorylated at Tyr1472. 2010/09
21.
原著(症例報告除く)
Involvement of prostaglandin F
2α
receptor in ATP-induced mechanical allodynia 2009/09
22.
原著(症例報告除く)
Translocation of neuronal nitric oxide synthase to the plasma membrane by ATP is mediated by P2X and P2Y receptors 2009/07
23.
原著(症例報告除く)
Characterization of signaling pathway for the translocation of neuronal nitric oxide synthase to the plasma membrane by PACAP. 2008/06
24.
原著(症例報告除く)
Involvement of stem cell factor and its receptor tyrosine kinase c-kit in pain regulation. 2008/06
25.
総説
【痛みのメカニズムとその制御】 痛みにおけるNOの関与 2008/05
26.
総説
脊髄後角におけるNMDA受容体リン酸化と神経因性疼痛 2007/11
27.
原著(症例報告除く)
Nitric oxide (NO) serves as a retrograde messenger to activate neuronal NO synthase in the spinal cord via NMDA receptors. 2007/08
28.
原著(症例報告除く)
Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQ. 2007/04
29.
原著(症例報告除く)
Interleukin-1 is not essential for expression of inducible NOS in hepatocytes induced by lipopolysaccharide in vivo. 2007/03
30.
原著(症例報告除く)
Cytotoxic effect of spermine on retinal pigment epithelial cells. 2007/01
31.
原著(症例報告除く)
In situ measurement of neuronal nitric oxide synthase activity in the spinal cord by NADPH-diaphorase histochemistry. 2006/01
32.
原著(症例報告除く)
The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E 2-induced allodynia, tactile pain associated with nerve injury 2006
33.
原著(症例報告除く)
Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype. 2005/12
34.
総説
プロスタグランジン受容体の機能・多様性と痛み機構 2005/12
35.
原著(症例報告除く)
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain. 2005/09
36.
原著(症例報告除く)
Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS). 2005
37.
原著(症例報告除く)
Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid. 2004
38.
原著(症例報告除く)
Characterization of N-methyl-D-aspartate receptor subunits involved in acute ammonia toxicity. 2004
39.
原著(症例報告除く)
Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain. 2004
40.
原著(症例報告除く)
Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production. 2003
41.
原著(症例報告除く)
Functional characterization of prostaglandin F2alpha receptor in the spinal cord for tactile pain (allodynia). 2003
42.
原著(症例報告除く)
Functional evidence for interaction between prostaglandin EP3 and kappa-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120. 2003
43.
原著(症例報告除く)
Prevention of ornithine cytotoxicity by nonpolar side chain amino acids in retinal pigment epithelial cells. 2003
44.
総説
生化学の立場からみた痛みの分子機構と治療 2002
45.
原著(症例報告除く)
Characterization of the glutamatergic system for induction and maintenance of allodynia. 2001
46.
原著(症例報告除く)
最新の生化学研究 安全なアスピリン 選択的COX-2阻害薬 2000/05
47.
原著(症例報告除く)
Identification of an abdominal ganglion neuron antagonizing L7-driven gill contraction in Aplysia 1999
48.
原著(症例報告除く)
Relationship between Energy-Dependent Macrounolecule Uptake and Transport Granules in the Endothelial Cells Affected by Wall Shear Stress. 1999
49.
原著(症例報告除く)
Serotonergic control of the heart and pericardium in the chiton
Acanthopleura japonica
. 1999
50.
原著(症例報告除く)
Effect of shear stress on macromolecule uptake into cultured endothelial cells. 1998
51.
原著(症例報告除く)
Superoxide dismutase mimic does not affect the early process of glutamate neurotoxicity in rat hippocampal culture. 1998
52.
原著(症例報告除く)
Production of reactive oxygen species and glutamate neurotoxicity in a rat organotypic hippocampal culture. 1997
53.
原著(症例報告除く)
Both the heart and pericardium in the chiton Acanthopleura japonica receive dual innervation from the central nervous system. 1996
54.
原著(症例報告除く)
Glutamate induces rapid nuclear changes in rat organotypic hippocampal culture: video enhanced contrast study. 1996
55.
原著(症例報告除く)
Spontaneous intracellular free calcium spikes induced by fluid flow application to cultured endothelial cells. 1996
56.
原著(症例報告除く)
Immunocytochemical and physiological studies of FMRFamide, catch-relaxing peptide and GWamide in the heart of molluscs. 1992
5件表示
全件表示(56件)
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著書
1.
部分執筆
痛みの可塑性と慢性化「脊椎脊髄ジャーナル 特集痛みとしびれのサイエンス─基礎と臨床」 2011/05
2.
その他
動物生理(1)-3.循環 無脊髄動物の心臓・循環系「生物学データ大百科事典 上巻」 2002
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学会発表
1.
Analysis of visceral pain transmission in the spinal dorsal horn using a dextran sodium sulfate-induced colitis model (ポスター掲示,一般) 2021/07/29
2.
発生および慢性疼痛下の一次知覚神経におけるRNA編集の変動
RNA editing in sensory neuron is regulated during development and pain conditions. (ポスター掲示,一般) 2017/12
3.
Impaired peripheral nerve regeneration in type 2 diabetic mouse model (ポスター掲示,一般) 2017/11
4.
Na+/K+-ATPase coupled to ETBR promotes peripheral nerve regeneration via lactate signaling (ポスター掲示,一般) 2017/11
5.
神経障害性および炎症性疼痛モデルにおけるRNA編集異常 (口頭,一般) 2017/09
6.
神経細胞特異的に蛍光タンパクを発現するマウスを用いた坐骨神経切断―再生モデルの確立と神経再生メカニズムの解析
Establishment of sciatic nerve transection-regeneration model with mice expressing fluorescence protein in neurons and analysis of its mechanisms (口頭,特別講演・招待講演など) 2017/06
7.
Involvement of Na
+
/K
+
-ATPase in peripheral nerve regeneration via lactate signaling in sciatic nerve transection-regeneration model. (ポスター掲示,一般) 2016/11
8.
Study on the effect of diabetic neuropathy on peripheral nerve regeneration in mouse model. (ポスター掲示,一般) 2016/09
9.
Chasing morphological changes of neuronal processes in the spinal dorsal horn in an inflammatory pain model by using two-photon microscopy. (ポスター掲示,一般) 2015/10
10.
Involvement of c-Jun N-terminal kinase in neurite extension of cultured DRG neurons. (ポスター掲示,一般) 2015/10
11.
Two feasible mouse models for neuropathy. (ポスター掲示,一般) 2015/09
12.
Involvement of endothelin B receptor in peripheral nerve regeneration using sciatic nerve transection-regeneration model. (口頭,一般) 2015/03
13.
Involvement of c-Jun N-terminal kinase in peripheral nerve regeneration. (ポスター掲示,一般) 2014/11
14.
Involvement of endothelin in peripheral nerve regeneration. (ポスター掲示,一般) 2014/11
15.
CaMKIIキナーゼ不活型KIマウスにおける慢性疼痛モデル脊髄後角のCaMKIIのシナプス局在 (ポスター掲示,一般) 2014/09
16.
In vivo カルシウムイメージングを用いた皮膚の異なる点への感覚刺激に応答する脊髄後角ニューロンの解析 (ポスター掲示,一般) 2014/09
17.
成熟した疼痛研究の新しい展開
New departure of mature pain research. (口頭,一般) 2014/07
18.
末梢神経再生モデルを用いた神経再生におけるエンドセリンの関与
Involvement of endothelin in peripheral nerve regeneration using tubing and osmotic pump model. (口頭,一般) 2014/06
19.
Synaptic localization of CaMKII in the spinal dorsal horn of kinase-dead knock-in mouse in the maintenance of neuropathic pain (ポスター掲示,一般) 2013/11
20.
Synaptic localization of CaMKII with mice model of chronic pain. (ポスター掲示,一般) 2013/06
21.
Three-dimensional distribution of sensory stimulation-evoked neuronal activity of spinal dorsal horn neurons analyzed by in vivo calcium imaging. In vivo カルシウムイメージングによる脊髄後角ニューロンの神経活動の三次元分布の解析 (ポスター掲示,一般) 2013/06
22.
Developmental regulation of RNA editing in mouse dorsal root ganglion. (ポスター掲示,一般) 2012/10
23.
Blockade of microglial migration in the spinal cord by prostaglandin E2 via EP2. (ポスター掲示,一般) 2011/11
24.
生体吸収性ハイドロゲルの手術創埋込みによる鎮痛薬の徐放効果を用いた革新的な術後鎮痛法の開発 (ポスター掲示,一般) 2011/07
25.
生体吸収性ゲルの手術創埋込みによる鎮痛薬の徐放効果を用いた新しい術鎮痛法 (口頭,一般) 2011/05
26.
Attenuation of neuropathic pain by impaired Ca
2+
signaling in mutant mice lacking the Tyr-1472 phosphorylation site of the NR2B. (ポスター掲示,一般) 2010/11
27.
Involvement of prostaglandin F
2α
receptor in ATP-induced mechanical allodynia. (ポスター掲示,一般) 2009/10
28.
Involvement of phosphorylation of NR2B subunit NMDA receptor at TYR 1472 in maintenance of neurophathic pain. (ポスター掲示) 2008/08
29.
1P-0889 PACAPシグナル伝達を介したnNOSの細胞膜への移動の分子機構 (ポスター掲示) 2007/12
30.
PACAPシグナル伝達を介した一酸化窒素合成酵素(nNOS)の機能調節の分子機構 (口頭) 2007/12
31.
Differentiation and migration of progenitor cells for maitenance of neuropathic pain in the model using nestin promoter-GFP transgenic mice. (ポスター掲示) 2007/11
32.
Molecular mechanism for the translocation of nNOS to the plasma membrane by PACAP (ポスター掲示) 2007/11
33.
Nitric oxide is involved in activation of neuronal nitric oxide synthase as a retrograde messenger in the spinal cord (ポスター掲示) 2007/11
34.
Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQ (ポスター掲示) 2007/11
35.
PACAPシグナル伝達を介したnNOSの機能調節の分子機構 (口頭) 2006/11
36.
Establishment of in situ analysis system of neuronal nitric oxide synthase activity in the spinal cord (ポスター掲示) 2006/10
37.
The opioid peptide neciceptin / orphanin FQ mediates prostaglandin E2-induced alllodynia, tactile pain associated with nerve injury (ポスター掲示) 2006/10
38.
NADPHジアホラーゼ組織染色による一酸化窒素合成酵素活性の可視化 (ポスター掲示) 2006/09
39.
Ornithine cytotoxicity for human pigment epithelial cells is mediated by cationic amino acid transporterⅠ(CAT-1) 2006/06
40.
Role of prostaglandin E receptor subtypes in nitric oxide production in the spinal cord. (ポスター掲示) 2005/11
41.
Mediation by the opioid peptide nociceptin/orphanin FQ of prostaglandin E-2-induced allodynia, tactile pain associated with never injury 2005/10
42.
Involvement of prostaglandin E2 in neuropathic pain through phosphorylation of nyristoylated alanine-rich C-kinase substrate by rho-kinase. 2005/08
43.
Diverse mechanisms of maintenance of chronic pain by prostaglandin E2 via different Ep subtypes. 2005/07
44.
神経損傷に伴うPACAPの発現誘導と疼痛発生機構 2005/03
45.
Acute and late effects on induction of allodynia by acromelic acid, a potent kainite analogue from a poisonous mushroom. 2004/10
46.
カイニン酸類似キノコ毒、アクロメリン酸の急性および遅延性アロディニア誘導効果 2004/09
47.
神経因性疼痛へのラマトロバンの鎮痛効果 2004/09
48.
Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production. 2003/11
49.
Functional evidence for interaction between prostaglandin EP
3
and k-opioid receptor pathways in tactile pain induced by human immunodeficiency virus type-1 (HIV-1) glycoprotein gp120. 2003/11
50.
Functional characterization of prostaglandin F2α receptor in the spinal cord for tactile pain (allodynia). (シンポジウム・ワークショップ パネル(指名)) 2003/10
51.
生化学・分子生物学的アプローチによる痛み研究の最近の進歩 2003/09
52.
脊髄における神経可塑性モデル-アロディニアの発生機構- 2003/08
53.
マウス術後痛モデルに対するザルトプロフェンの効果 2003/06
54.
生物新機能と創薬をめざす生体内分子科学—新規ノシセプチン受容体拮抗薬を用いた内在性ノシセプチンの慢性痛への関与の検証— 2003/01
55.
慢性痛とは何かー基礎医学の立場より 2003/01
56.
神経因性疼痛におけるノシセプチンの関与 2002/10
57.
脊髄の痛覚伝達におけるグルタミン酸の役割 2001/10
5件表示
全件表示(57件)
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研究の専門分野
神経科学一般, 医療薬学, 神経科学一般, 医化学
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研究手法
イメージング、 電気生理学